Asymmetric Catalysis
Rhodium-catalysed asymmetric allylic arylation of racemic halides with arylboronic acids.
M. Sidera and S. P. Fletcher
Non-stabilized nucleophiles in Cu-catalyzed dynamic kinetic asymmetric allylic alkylation.
H. You, E. Rideau, M. Sidera and S. P. Fletcher
Formation of quaternary centers by copper-catalyzed asymmetric conjugate addition of alkylzirconium reagents.
M. Sidera, P. M. C. Roth, R. M. Maksymowicz and S. P. Fletcher
Angew. Chem. Int. Ed. 2013,
52,
7995–7999.
‘hot paper’
Catalytic asymmetric carbon-carbon bond formation using alkenes as alkylmetal equivalents.
R. M. Maksymowicz, P. M. C. Roth and S. P. Fletcher
Self-Replicating Systems
Visualization of the spontaneous emergence of a complex, dynamic, and autocatalytic system.
J. Ortega-Arroy, A. J. Bissette, P. Kukura and S. P. Fletcher
Proc. Natl. Acad. Sci. U. S. A. 2016, 113,
11122-11126.
Physical autocatalysis driven by a bond-forming thiol-ene reaction.
A. J. Bissette, B. Odell and S. P. Fletcher
Nature Communications 2014,
5,
4607.
Mechanisms of autocatalysis.
A. J. Bissette and S. P. Fletcher
Synthetic engineering of potential energy surfaces
Barrierless photoisomerization of 11-cis retinal protonated Schiff Base in solution.
G. Bassolino, T. Sovdat, A. Soares Duarte, J.-M. Lim, C. Schnedermann, M. Liebel, B. Odell, T. D. W. Claridge, S. P. Fletcher and P. Kukura
Synthetic control of retinal photochemistry and photophysics in solution.
G. Bassolino, T. Sovdat, M. Liebel, C. Schnedermann, B. Odell, T. D. W. Claridge, P. Kukura and S. P. Fletcher
Backbone modification of retinal induces protein-like excited state dynamics in solution.
T. Sovdat, G. Bassolino, M. Liebel, C. Schnedermann, S. P. Fletcher and P. Kukura
Molecular Machines
Conversion of light into macroscopic helical motion.
S. Iamsaard, S. J. Aβhoff, B. Matt, T. Kudernac, J. J. L. M. Cornelissen, S. P. Fletcher and N. Katsonis