Fletcher Research Group

50) Copper-catalysed asymmetric allylic alkylation of alkylzirconocenes to racemic 3,6-dihydro-2H-pyrans.
E. Rideau and S. P. Fletcher
Beilstein J. Org. Chem. 2015, 11, 2435–2443.
 
 
 
49) Rhodium-catalysed asymmetric allylic arylation of racemic halides with arylboronic acids.
M. Sidera and S. P. Fletcher
Nature Chem. 20157935-939.
 
 
 
48) Barrierless photoisomerization of 11-cis retinal protonated Schiff Base in solution.
G. Bassolino, T. Sovdat, A. Soares Duarte, J.-M. Lim, C. Schnedermann, M. Liebel, B. Odell, T. D. W. Claridge, S. P. Fletcher and P. Kukura
J. Am. Chem. Soc. 201513712434–12437.
 
 
 
47) An alternative synthesis of the breast cancer drug Fulvestrant (Faslodex): Catalyst control over C-C bond formation.
D. Caprioglio and S. P. Fletcher
Chem. Commun. 20155114866–14868
 
 
 
46) Profile: Early excellence in physical organic chemistry.
S. P. Fletcher
J. Phys. Org. Chem. 2015, 28713.
 
45) Asymmetric conjugate additions of alkylzirconocenes to cyclopent-4-ene-1,3-dione monoacetals.
E. Rideau, F. Mäsing and S. P. Fletcher
Synthesis 2015, 47, 2217–2222.
Highlighted in Synfacts 2015, 11, 1163.
Special Topic on Conjugate Addition Reactions
 
44) Simple azo dyes provide access to versatile chiroptical switches.
E. Anger and S. P. Fletcher
Eur. J. Org. Chem. 20153651–3655.
 
43) Cu-catalyzed asymmetric addition of sp2-hybridized zirconium nucleophiles to racemic allyl bromides.
M. Sidera and S. P. Fletcher
Chem. Commun. 2015, 515044–5047
Highlighted in Synfacts 2016, 11, 614.
 
 
 
42) Novel applications of physical autocatalysis
A. J. Bissette and S. P. Fletcher
Orig. Life. Evol. Biosph. 20154521-30.
 
41) Enantioselective copper(I)-phosphoramidite catalyzed addition of alkylzirconium species to acyclic enones.
P. M. C. Roth and S. P. Fletcher
Org. Lett. 201517912–915.
 
 
 
40) Asymmetric conjugate additions and allylic alkylations using nucleophiles generated by hydro- or carbometallation.
R. M. Maksymowicz, A. J. Bissette and S. P. Fletcher
Chem. Eur. J. 2015215668–5678
 
39) Non-stabilized nucleophiles in Cu-catalyzed dynamic kinetic asymmetric allylic alkylation.
H. You, E. Rideau, M. Sidera and S. P. Fletcher
Nature 2015, 517351–355.
 
 
 
38) Systems chemistry: Selecting complex behaviour

A.J. Bissette and S. P. Fletcher

Nature Chem. 2015715-17.
 
37) Asymmetric remote C-H functionalization: use of internal olefins in tandem hydrometallation-isomerization-asymmetric conjugate addition sequences.
L. Mola, M. Sidera and S. P. Fletcher
Aust. J. Chem. 201568401-403.
Professor Richard (Rick) Frances Langler Memorial Issue.
 
 
 
 
36) Physical autocatalysis driven by a bond-forming thiol-ene reaction. 
A. J. Bissette, B. Odell and S. P. Fletcher
Nature Commun. 2014, 5, 4607.
 
 
35) Asymmetric conjugate additions of alkylzirconium reagents to α,β-unsubstituted lactones.
E. E. MacIver, R. M. Maksymowicz, N. Wilkinson, P. M. C. Roth and S. P. Fletcher
Org. Lett. 2014, 16, 3288-3291.   ACS Editors Choice
Highlighted in Synfacts 2014, 10, 946.
 
 
 
34) Conversion of light into macroscopic helical motion.
S. Iamsaard, S. J. Aβhoff, B. Matt, T. Kudernac, J. J. L. M. Cornelissen, S. P. Fletcher and N. Katsonis

Nature Chem. 2014, 6, 229-235.
 
Highlights:
C&E News 2014, volume 92 issue 6, pg. 27
Chemistry World, 10 February 2014
 
 
 
33) Synthetic control of retinal photochemistry and photophysics in solution.
G. Bassolino, T. Sovdat, M. Liebel, C. Schnedermann, B. Odell, T. D. W. Claridge, P. Kukura and S. P. Fletcher
J. Am. Chem. Soc. 2014, 136, 2650-2658.
 
 
 
32) Copper-catalyzed asymmetric conjugate addition of alkylzirconium reagents to cyclic enones to form quaternary centers.
P. M. C. Roth, M. Sidera, R. M. Maksymowicz and S. P. Fletcher 

Nature Protoc. 2014, 9, 104–111.
 
31) A. J. Bissette and S. P. Fletcher. Hydrogenolysis of allyl and benzyl halides and related compounds. In: Gary A. Molander and Paul Knochel (eds.), Comprehensive Organic Synthesis, 2nd edition, Vol 8, Oxford; Elsevier; 2014. pp. 1164-1184.
 
30) V. E. Ziffle and S.P. Fletcher. Reduction of saturated alkyl halides to alkenes. In: Gary A. Molander and Paul Knochel (eds.), Comprehensive Organic Synthesis, 2nd edition, Vol 8, Oxford; Elsevier; 2014. pp. 999-1010.